Purine nucleotides
Medchemexpress LLC Adenosine 5'-monophosphate | 61-19-8 | MFCD00149360 | 99.8% | 347.22 | C10H14N5O7P | 10 MG
Adenosine 5'-monophosphate (AMP) is a nucleotide involved in cellular energy transfer and signal transduction. This research-grade biochemical is supplied as a solid or solution and is intended for in vitro research applications; the manufacturer lists high purity and molecular weight of 347.22 g/mol.
- High purity (99.8%) suitable for research use
- Defined molecular weight of 347.22 g/mol
- Available as solid and as DMSO solution for flexible use
- Commonly used in biochemical assays and receptor pharmacology studies
- Provided with supporting documentation such as datasheets and COA when available
Medchemexpress LLC Adenosine receptor antagonist 2 | 2703054-47-9 | 99.4% | C23H21FN8O | 25 MG
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. It exhibits anti-tumor activity and has been shown to inhibit tumor growth in vivo.
- Orally active A2a/A2b adenosine receptor antagonist
- Potent inhibition: IC50s of 1 nM (A2a) and 3 nM (A2b)
- Exhibits anti-tumor activity
- Inhibits tumor growth in female C57BL/6 mice
- Molecular weight: 444.46
Medchemexpress LLC Adenosine monophosphate | 61-19-8 | MFCD00655082 | 99.7% | C10H14N5O7P | 25 MG
Adenosine monophosphate is provided as an analytical standard, suitable for a variety of research and analytical applications. It functions as an adenosine A1 receptor agonist and exhibits significant antiviral activity against HSV-1 and HSV-2. As a key cellular metabolite, it plays a role in regulating energy homeostasis and signal transduction.
- Intended for research and analytical applications
- Functions as an adenosine A1 receptor agonist
- Possesses significant antiviral activity against HSV-1 and HSV-2
- Key cellular metabolite regulating energy homeostasis and signal transduction
- Used in qualitative, quantitative, and methodological research experiments
- Suitable for techniques such as HPLC, GC, and MS
Medchemexpress LLC Adenosine receptor inhibitor 2 | 2550401-76-6 | 99.1% | 406.28 | 25 MG
Adenosine receptor inhibitor 2 (compound 14b) is a potent AR (adenosine receptor) inhibitor that exhibits dual affinity toward A1/A2A ARs, with a higher affinity for A1AR than A2AAR. It has Ki values of 52.2 nM for A1AR and 167 nM for A2AAR.
- Potent AR inhibitor.
- Dual affinity for A1/A2A adenosine receptors.
- Ki values of 52.2 nM for A1AR.
- Ki values of 167 nM for A2AAR.
- Targeted receptors include A1AR, A2AR, hA2B, and Adenosine A3 receptor.
- Purity of 99.08%.
- Molecular weight of 406.28.
- Appearance as a white to off-white solid.
Medchemexpress LLC Mtb ATP synthase-IN-1 | 2642394-38-3 | 98.6% | C17H13N3O4 | 10MG
Mtb ATP synthase-IN-1 is a potent Mycobacterium tuberculosis ATP synthase inhibitor (compound 6ab) for anti-mycobacterial research. It exhibits MIC 0.452-0.499 μg/mL against M. tuberculosis, demonstrates good metabolic stability and acceptable oral bioavailability, and shows low cytotoxicity in Vero cells.
- Potent inhibition of M. tuberculosis ATP synthase
- MIC 0.452-0.499 μg/mL against M. tuberculosis
- Good metabolic stability
- Low cytotoxicity (Vero IC50 > 64 μg/mL)
- High purity (~98.6%)
- Available in multiple solid and solution pack sizes
- Stable storage recommendations for powder and solutions
Medchemexpress LLC Adenosine-13C5 | 159496-13-6 | 99.9% | 5 MG
Adenosine-13C5 is a 13C labeled form of Adenosine, a ubiquitous endogenous autacoid that plays a crucial role in cellular physiology. It acts through four G protein-coupled receptors (A1, A2A, A2B, and A3) and influences processes such as neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Isotopically enriched to 99%.
- Affects nearly all aspects of cellular physiology.
Medchemexpress LLC Recombinant human adenosine kinase | >95.0% | 50 UG
Recombinant human adenosine kinase (ADK) is a full-length, tag-free enzyme produced in HEK293 cells for biochemical and enzymatic research. Supplied as a filtered solution with stabilizers, it offers consistent activity and low endotoxin for reliable assay results.
- Full-length human sequence (M1-H345).
- Expressed in HEK293 mammalian cells for native folding.
- Tag free to minimize assay interference.
- Purity >95% as determined by reducing SDS-PAGE.
- Formulated in 20 mM Tris, 300 mM NaCl, pH 8.0, with stabilizers and 20% glycerol.
- Endotoxin <1 EU/μg and measured specific activity for activity-based assays.
- Supplied as a frozen solution and shipped on dry ice to preserve activity.
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5'-triphosphate disodium salt hydrate Grade II, >=97% (HPLC), crystalline, from microbial | 34369-07-8 | MFCD00150755 | 1G
Adenosine 5'-triphosphate disodium salt hydrate Grade II, >=97% (HPLC), crystalline, from microbial | Purity: >=97% (HPLC) | 34369-07-8 | MFCD00150755 | 1G
Apexbio Technology LLC 7-Deaza-ATP(Synonyms: 7-Deazaadenosine triphosphate, 7-Deaza-ATP, 7-Deazaadenosine-5'-triphosphate), 50ul (100 mM).
7-Deaza-ATP is a chemically modified ATP analog wherein the nitrogen atom at position 7 of the adenine ring is replaced by a carbon atom This structural alteration modulates its interactions with enzymes and nucleic acid-binding proteins As a nucleotide analog 7-Deaza-ATP can be incorporated into DNA and RNA strands thereby influencing polymerase enzyme activity and subsequently affecting nucleotide synthesis replication and repair processes Due to these properties this molecule is applied in investigating nucleotide-protein binding specificity and the catalytic mechanisms of enzymes facilitating research towards nucleotide-targeted therapeutic strategies
Cambridge Isotope Laboratories Guanosine phosphoramidite (U-13C10 98% U-15N5 98%) CP 95% 50 mg
Guanosine phosphoramidite (U-13C10 98% U-15N5 98%) CP 95% 50 mg
Medchemexpress LLC Adenosine antagonist-1 | 431040-19-6 | 99.8% | 359.41 g/mol | C18H13N7S | 25 MG
Adenosine antagonist-1 is a small-molecule adenosine A3 receptor (A3R) antagonist reported to have anti-inflammatory activity for in vitro and preclinical research. The compound is supplied as a white to off-white solid with molecular formula C18H13N7S and molecular weight 359.41 g/mol. Typical purity is 99.79% and the material is provided in milligram-scale quantities for laboratory studies.
- Acts as an adenosine A3 receptor antagonist with anti-inflammatory activity.
- High chemical purity (99.79%) suitable for research applications.
- Molecular formula C18H13N7S; molecular weight 359.41 g/mol.
- Available in milligram-scale quantities for in vitro and preclinical studies.
- Supplied as a white to off-white solid for easier handling and storage.
Medchemexpress LLC 3H-imidazo[4,5-b]pyridine, 2-ethyl-5,7-dimethyl- | 133240-06-9 | 99.4% | 175.24 g/mol | C10H13N3 | 50 MG
Adenosine receptor antagonist 4 (compound 2) is a small-molecule adenosine A1 receptor antagonist reported with a Ki of 101 nM for the human A1 receptor. It is provided for research use and is characterized by a defined molecular formula and high purity suitable for in vitro pharmacology and receptor-binding studies.
- Cas number 133240-06-9.
- Molecular formula C10H13N3 and molecular weight 175.24 g/mol.
- Purity (HPLC) 99.35%.
- Available in solution (10 mM in DMSO) and solid sizes including 25 mg, 50 mg, and 100 mg.
- Batch-specific COA, data sheet, and SDS are available for handling and quality information.
Medchemexpress LLC 3-(5-(2-methyl-1H-imidazol-1-yl)-2-(pyrazin-2-ylamino)thiazol-4-yl)benzonitrile | 431040-19-6 | MFCD30747838 | 99.8% | 359.41 | C18H13N7S | 100 MG
Adenosine antagonist-1 is a research-grade small-molecule antagonist of the adenosine A3 receptor (AA3R) with reported anti-inflammatory activity. It is supplied as a solid powder and as a 10 mM solution in DMSO for use in biochemical, cellular, and preclinical studies; molecular formula C18H13N7S, molecular weight 359.41, CAS 431040-19-6.
- Selective adenosine A3 receptor antagonism for receptor biology studies.
- Reported anti-inflammatory activity in preclinical models.
- Available as solid powder or 10 mM solution in DMSO for flexible dosing.
- High purity suitable for biochemical and cellular assays.
- Molecular formula and weight provided for formulation and dosing calculations.
Medchemexpress LLC Guanosine 5'-triphosphate-5'-adenosine triammonium | 00-00-0 | 100.0% | 823.50 | C20H36N13O17P3 | 5 MG
Guanosine 5'-triphosphate-5'-adenosine triammonium is a 5′ cap analog and fluorescent substrate analog used in vitro for RNA synthesis and enzymatic assays. It is supplied as a high-purity triammonium salt in small-mass vials for research applications.
- Cap analog for in vitro RNA synthesis.
- Fluorescent substrate analog suitable for enzymatic assays.
- High purity for reproducible experimental results.
- Available in multiple small sizes, including 5 mg vials.
- Molecular weight provided for accurate molarity calculations.
- Triammonium salt form enhances aqueous solubility.
Research Products International Corp Adenosine 1.5 KG
Substance Name: 9-β-D-Ribofuranosyladenine
CAS Number: 58-61-7
Molecular Formula: C10H13N5O4
Molecular Weight: 267.2